Vascular calcification is a serious issue that often accompanies atherosclerosis, leading to significant cardiovascular complications. While current treatments focus on slowing down the progression of calcification, there is limited success in fully reversing the process. EDTA chelation therapy is currently considered the best option, although its efficacy is debated in the medical community. Understanding the underlying mechanisms of calcification, including active and passive processes, is crucial for developing more effective treatments. Monitoring phosphate and pyrophosphate levels in the blood, and implementing targeted therapies to address any imbalances, can help prevent and manage vascular calcification. For more information on this topic, you can refer to the article “Considering the Mechanisms of Vascular Calcification – Fight Aging!” at the following link: https://doi.org/10.3390/biology13020111.