Researchers at Washington University in St. Louis have made a significant discovery about the aging of metabolism in mice. They found that the activity of Ppp1r17 in the hypothalamus of the brain plays a key role in the aging process. This affects the sympathetic nervous system and leads to reduced innervation of fat tissue, ultimately impacting the availability of nutrients and signal molecules in the body. The researchers also identified potential intervention points to prevent this decline, offering hope for anti-aging therapies in the future. For more information, you can read the full article here: https://medicine.wustl.edu/news/life-span-increases-in-mice-when-specific-brain-cells-are-activated/