UW-Madison Gets $150M Grant for National Dementia Study 

The University of Wisconsin-Madison has been awarded a $150 million grant from the National Institutes of Health to lead a nationwide study on Alzheimer’s disease and related dementias. The study, known as the Clarity in Alzheimer’s Disease and Related Dementias Research Through Imaging (CLARiTI), is a five-year initiative that aims to enhance the understanding of the neurobiology of these conditions. Led by UW-Madison Professor Sterling Johnson, the study will involve all 37 of the Alzheimer’s Disease Research Centers in the U.S., with a focus on investigating the imaging and biomarkers relevant to Alzheimer’s and mixed dementia. By collaborating across the network of research centers, the study aims to advance the understanding and treatment of dementia. In addition to the 17,000 participants already involved in research across the country, the CLARiTI study will add 2,000 more participants at various locations nationwide. This collaborative effort will address critical research gaps and pave the way for future uniform blood-biomarker characterization in the Alzheimer’s Disease Research Centers. The study represents a significant milestone in dementia research and is expected to shed new light on the complex interplay of multiple pathologies that contribute to dementia.