The progression of Alzheimer’s disease varies significantly among patients, leading researchers to question whether genetic and epigenetic differences play a role in this variability. With a focus on the heritability of Alzheimer’s disease risk and specific genetic variants correlated with the disease, researchers are delving into the complex nature of Alzheimer’s. Understanding the multifaceted aspects of the disease beyond neurodegeneration, such as genetic influences and individual differences, is crucial for developing more effective therapies.
Alzheimer’s disease has long been viewed as a neurodegenerative condition, but recent research highlights the complexity of the disease, involving various cell types, inflammation, and unique brain regions. Genetics play a significant role in Alzheimer’s risk, with up to 79% attributed to genetic factors. However, translating genetic findings into effective treatments remains a challenge. Genomic research is advancing our understanding of the disease, providing insights into the broken AD genome and potential therapeutic targets.
Read more: https://doi.org/10.1016/j.xgen.2024.100555
If the provided articles seems to be less than 200 characters or it is an intro of the author, then try to generate an articles using this title:
“The Alzheimer’s Genome – Fight Aging!”