Rheumatoid arthritis is a medical condition that is influenced by the processes of aging, but it is not commonly considered an age-related disease. This aspect is discussed in an open access commentary and the related paper, which highlights the need for a better mechanistic understanding of the condition. Treatments for rheumatoid arthritis currently focus on suppressing chronic inflammatory dysfunction, with potential long-term side effects. Recent research has shown that biological aging plays a significant role in the development and progression of rheumatoid arthritis, impacting life expectancy and quality of life. Understanding and managing biological aging could be a promising approach to enhancing the lifespan and well-being of individuals with rheumatoid arthritis, regardless of their chronological age. Further investigations are needed to explore the potential differences in the effects of accelerated biological aging on life expectancy between men and women with rheumatoid arthritis.