Dysfunction of the salivary gland is a commonly overlooked issue in aging individuals. However, new research has shown that injecting platelet rich plasma into the salivary gland can effectively restore function in older mice. This treatment promotes cell regrowth, reduces inflammation, and decreases cellular senescence in the gland. The use of platelet rich plasma in regenerative medicine has been well-established, and this study further supports its effectiveness in an animal model.
Saliva, produced by the salivary glands, is crucial for maintaining oral health and function. Dysfunction of the salivary glands can lead to various complications, including dry mouth, inflammation, and dental issues. This study investigated the use of platelet rich plasma to prevent age-related salivary gland dysfunction and found promising results in rejuvenating salivary gland function.
The research examined the effects of injecting the supernatant of activated platelet rich plasma into the salivary glands and found that it significantly reduced cellular senescence, apoptosis, and inflammation. In aged mice, the treatment improved salivary flow rate and structural tissue remodeling. This study provides valuable insights into potential treatments for age-related salivary gland dysfunction.
