Moving the STING Gene from Long-Lived Bats into Short-Lived Mice, Reducing Age-Related Inflammation – Fight Aging!

Researchers have started transferring genes from long-lived species into short-lived species to study the comparative biology of aging. A recent study involved moving a naked mole-rat cancer resistance gene into mice. In a new study, researchers moved the STING gene from long-lived bats into mice. STING plays a role in innate immune sensing and is linked to chronic inflammation in aging. Bats are known for their resilience to viral infections, suggesting their genes may provide protection against inflammation in mammals. The research showed that introducing the bat STING gene into mice reduced aging-related inflammation, potentially improving healthspan. This study sheds light on the mechanisms behind bat longevity and could offer insights into healthy aging in humans.