MKK4 Inhibition Provokes Greater Liver Regeneration
Researchers have discovered a novel approach to enhance liver regeneration by inhibiting MKK4. This method specifically targets the liver’s regrowth capacity, showing promising results in both murine and porcine models. The development of small molecule inhibitors of MKK4 has paved the way for potential treatments to prevent liver failure after extensive surgeries or transplants. Clinical trials are underway to explore the therapeutic benefits of this approach. Link: https://doi.org/10.1016/j.cell.2024.02.023
