Features of the Gut Microbiome Correlating with Osteoporosis Risk
The gut microbiome composition changes with age and plays a role in aging. A microbiome with more inflammatory microbes and fewer beneficial ones can be harmful in the long term. Researchers can now accurately measure microbial species in the gut to study how specific microbes impact age-related conditions like osteoporosis, which is the loss of bone density with age.
Osteoporosis is a major health concern affecting the aging population globally. Recent studies have highlighted the connection between gut microbiota and bone metabolism, offering new insights into the link between gut microbes and osteoporosis.
Using Mendelian randomization, this study explores the relationship between 211 types of gut microbes and osteoporosis. Data from genome-wide association studies and genetic databases reveal that some microbial species, like Coprococcus3, may have a protective effect against osteoporosis, while others could be positively correlated with the condition. This research provides important insights into the role of gut microbiome in osteoporosis development and progression.
