Aortic aneurysms are a serious health concern, with a high mortality rate once ruptured. Chronic inflammatory signaling has been identified as a key factor in the development of these aneurysms. Inflammatory cells release cytokines that lead to the degradation of the aortic wall, ultimately resulting in the destabilization of the vessel. Researchers are investigating the role of inflammasome regulation in the progression of aortic aneurysms, with the goal of identifying potential drugs for treatment beyond surgical methods. This research aims to provide new insights into the prevention and management of aortic aneurysms.