Building Biological Age Clocks from Immune and Redox Markers – Fight Aging!
The use of immune function and redox markers for estimating biological age (BA) is an important area of research, but it is crucial to understand how these assessments relate to the underlying processes of aging. Developing standardized biological age clocks will enable a better understanding of age-related damage and facilitate the development of targeted therapies for aging. A recent study constructed two mathematical models, the Immunity and Redox Clocks, to quantify BA in mice. These models showed strong correlation with chronological age and were validated in healthy and prematurely aging mice, demonstrating their potential utility in quantifying BA and its relationship to lifespan. This research represents an important step in the ongoing effort to develop reliable biological age clocks.