Advocates for the treatment of aging argue that aging and age-related disease are indistinguishable. Aging is a continuous process of decline in function, leading to disease. The subclinical stage of a disease is still damaging, and age-related diseases are just manifestations of aging. Researchers suggest testing age-slowing approaches in patients with conditions like Alzheimer’s disease, as promising interventions like calorie restriction have not been thoroughly studied in this population. Understanding aging as a target for preventing and treating Alzheimer’s is crucial, as aging is the primary risk factor for many diseases, including dementia.
Current treatments for Alzheimer’s manage symptoms but come with challenges. By targeting aging directly, it may be possible to prevent or slow multiple age-related diseases, including Alzheimer’s. Further research is needed to explore the mechanisms of calorie restriction and develop new therapeutic targets. Strategies that target aging may offer safer and more effective alternatives to current treatments. Including biomarkers of aging in Alzheimer’s trials and vice versa may provide valuable insights and potential treatment options.
