Butyrate is a beneficial metabolite produced by gut microbes in response to dietary fiber. Research shows it upregulates BDNF expression, supporting neurogenesis and mitochondrial quality. Aging is linked to decreased butyrate and BDNF levels, affecting neurogenesis and other processes. Restoring a youthful gut microbiome can help improve these issues. Butyrate has also been found to reduce sympathetic activation and improve cardiac function in rats with heart failure by inhibiting microglial inflammation in the brain.
The Benefits of Butyrate Include a Reduction in Microglial Inflammation in the Brain – Fight Aging!
