Recent research has shown that transferring planarian regeneration-associated genes into flies can slow intestinal aging, but at the cost of disrupting normal regeneration processes. This study highlights the early stages of cross-species gene transfer for understanding gene functions, rather than as a potential therapy. While this approach shows promise in improving intestinal function in aging flies, challenges remain in translating this research into enhancement therapies. Biochemistry complexities and multi-faceted effects of genetic changes complicate the path towards therapies for aging-related issues.