More on NNMT Inhibitors as a Basis for Treating Sarcopenia – Fight Aging!

Sarcopenia, the progressive loss of muscle mass and strength with age, is a complex process involving various mechanisms such as protein intake, neuromuscular dysfunction, and loss of muscle stem cell activity. Researchers have found that inhibiting NNMT in aging mice can increase muscle mass and strength, offering a potential treatment for sarcopenia. The development of small molecule NNMT inhibitors shows promise in enhancing the effects of resistance exercise on muscle. Recent studies demonstrate the positive impact of NNMT inhibition on muscle function in aged mice, indicating its potential as a treatment for sarcopenia and other age-related myopathies.