Liver Inflammation Contributes to Brain Inflammation
Chronic, unresolved inflammation is a hallmark of aging and can have detrimental effects on overall health. Inflammatory signals from one organ can spread throughout the body, leading to inflammation in other organs. This interconnectedness highlights the importance of addressing inflammation to maintain health as we age.
Research using an aging mouse model has shown that chronic inflammation in the liver, caused by necroptosis, can also impact brain health. Inhibiting necroptosis reduced liver damage and lowered brain inflammation, improving cognitive function in mice. The findings suggest a link between liver health, systemic inflammation, and cognitive impairment.
The study emphasizes the significance of organ crosstalk in disease research and highlights the need for targeted treatments to address inflammation in aging. By understanding the interconnectedness of organs and inflammation, new therapeutic approaches can be developed to combat age-related diseases.
Link: https://www.ouhsc.edu/News/details/organ-crosstalk-extends-harms-of-inflammation-from-liver-to-brain
