Mitochondria are essential for cell function, producing ATP to power cellular activities. As we age, mitochondrial dysfunction occurs due to DNA damage and changes in gene expression, leading to various stressors on cells. Researchers explore restoring mitochondrial function to combat aging, focusing on the ovaries.
Ovarian aging is a complex process involving the decline in oocyte quantity and quality. This impacts fertility, pregnancy risks, hormonal balance, bone health, cardiovascular well-being, and cognitive function. Mitochondria play a crucial role in energy production, particularly in oocytes, affecting reproductive success. Targeting mitochondrial health could delay aging and enhance reproductive outcomes in women.
This review delves into the link between mitochondrial function and ovarian aging, highlighting how preserving mitochondrial health can impact fertility decline with age. Therapeutic strategies focused on maintaining mitochondrial function offer promising opportunities for women’s reproductive and overall well-being.
