Recent research has shed light on the complex relationship between folate intake and aging, challenging the conventional wisdom that more folate is always better. Older animals with reduced folate levels showed improved metabolic flexibility and maintained their weight and body fat into old age, suggesting potential benefits similar to those seen with calorie restriction. This unexpected finding has led researchers to explore new avenues for optimizing folate intake in different age groups, potentially paving the way for personalized dietary recommendations and drug development. For more information, check out the full article here.