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Article Highlights:
– Autophagy is a key process linked to extending lifespan through calorie restriction and other stressors in lab animals.
– New drugs targeting autophagy, like mTOR inhibitors, show promise in slowing cellular aging and reducing the burden of senescent cells.
– Mitophagy, the recycling of damaged mitochondria, is crucial for maintaining cellular health and addressing age-related conditions like neurodegenerative diseases.
– The industry focus on small molecule therapies may not lead to significant advances in human longevity, highlighting the importance of exploring new research avenues for potential breakthroughs in aging treatment.
Read more about the latest developments in autophagy and mitophagy: https://www.fightaging.org/archives/2024/09/
Join the conversation on using combination therapies to treat aging and target multiple hallmarks of aging simultaneously: https://www.fightaging.org/archives/2024/09/thoughts-on-combination-therapies-to-treat-aging/
