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In this issue, we delve into the topic of epigenetic clocks and their significance in aging research. These clocks use machine learning to analyze changes in gene expression regulation that occur with age, providing insights into chronological and biological age. Understanding the limitations of these clocks is crucial, as it impacts their reliability in assessing the effects of potential rejuvenation therapies, such as senolytic treatments.
Additionally, researchers are encouraged to consider the broader implications of epigenetic aging on overall health outcomes. By contextualizing the results and avoiding generalizations based on blood samples alone, we can gain a more holistic view of the aging process.
Lastly, we explore the debate surrounding geroscience research and development, highlighting the importance of identifying effective strategies for extending human lifespan. While traditional pharmacological approaches may fall short, the Repair viewpoint of aging offers promising solutions by targeting specific forms of cell and tissue damage.
To read more on these topics and stay informed on the latest in aging research, visit Fight Aging! at: https://www.fightaging.org/newsletter/
