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In a recent study, the process of clearing microglia – innate immune cells in the central nervous system – was shown to improve the environment of a damaged retina in a mouse model of age-related macular degeneration. This approach, utilizing CSF1R inhibitors, has shown promising results in reducing inflammation and cellular senescence associated with neurodegenerative conditions. Read more about this fascinating research here: https://www.fightaging.org/archives/2024/05/clearance-of-microglia-as-a-treatment-for-macular-degeneration/
Additionally, our review paper examines the relationship between aging and cancer, exploring the common biological basis and mechanisms that link these two processes. While cancer risk typically increases with age due to mutational damage and immune system decline, there is evidence to suggest that very old age may actually see a decline in cancer incidence due to reduced cellular activity. Learn more about the complex interplay between aging and cancer in our detailed analysis: https://www.fightaging.org/archives/2024/05/why-is-cancer-an-age-related-disease/
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