Mitochondria, the powerhouse of cells, play a crucial role in generating energy for cellular functions. However, as we age, mitochondrial function deteriorates due to DNA damage and changes in gene expression. This decline is linked to degenerative aging, affecting tissues with high energy demands like the brain and muscles. Neurodegenerative diseases are often associated with mitochondrial dysfunction, highlighting the importance of maintaining mitochondrial health for overall well-being.
Neurodegenerative diseases impact millions worldwide, with mitochondrial dysfunction being a common factor in various conditions. Aging exacerbates neurodegenerative processes, contributing to cognitive and motor impairments. Mitochondrial issues are prevalent in diseases like Alzheimer’s and Parkinson’s, underscoring the need to address mitochondrial health in combating these conditions. Research into mitochondrial therapeutics shows promise in slowing down disease progression and aging.
Link: https://doi.org/10.4103/NRR.NRR-D-23-02106
