Biologics, Biosimilars and Generics: What’s the Difference?

What are biologics?

Biologics are medications derived from living materials such as plant cells, animal cells, and microorganisms like bacteria and yeast. They are used to treat a variety of health conditions including diabetes, arthritis, multiple sclerosis, and certain types of cancer.

What are biosimilars?

Biosimilars are biological drugs made from the same living materials as biologics and are designed to match already approved biological drugs. They are similar to the original biologic but typically more affordable for patients.

What are generics?

Generics are drugs that contain the same chemicals as brand name drugs. They must be approved by the FDA and meet the same standards as the brand name drug in terms of dosage form, safety, strength, quality, and intended use.

Biosimilars vs. Generics: Are they the same thing?

Can a pharmacist substitute a biosimilar for a biologic?

If a biosimilar is interchangeable, a pharmacist can substitute it for a biologic without consulting the healthcare provider. If not, permission is required before substitution.*

*State regulations may vary.

Considering switching from a biologic to a biosimilar for cost savings? Consult your healthcare provider for guidance. This informative content was made possible with support from Sandoz.