Senescent Microglia are Likely Important in Age-Related Neurodegeneration
Recent studies suggest that senescent microglia play a crucial role in age-related neurodegeneration. The accumulation of senescent cells in the brain, coupled with inefficient clearance due to immune system decline, leads to a pro-inflammatory environment that disrupts tissue function. Misfolded proteins are a common feature in neurodegenerative diseases, contributing to the complexity of disease onset and progression. Targeting microglial senescence through innovative therapies could offer new solutions for treating these age-related conditions. For more information, you can read the full article here.
