Mutation in the Context of Allotopic Expression of Mitochondrial DNA – Fight Aging!

Mitochondria, the powerhouse of the cell, play a crucial role in producing ATP, necessary for cell function. Mitochondria have their own DNA and are susceptible to damage, leading to dysfunctional cells. Researchers are exploring solutions, including allotopic expression, to create backup copies of mitochondrial genes in the nucleus. This technique aims to protect against mutations in mitochondrial DNA and prevent age-related decline in mitochondrial function. Despite potential challenges, allotopic expression shows promise in combating mitochondrial mutations and preserving cellular health.