What Harms are Caused Elsewhere in the Body by the Aging of the Brain? – Fight Aging!

A critical aspect of aging involves the dysregulation of interconnected control and feedback systems within the body. This disruption can lead to harmful effects on various organs as they age. Studies have shown that longevity is influenced by signaling pathways originating from neurons in the central nervous system. These pathways can impact the health and lifespan of organisms by transmitting signals to peripheral tissues. In different organisms like nematode worms and fruit flies, specific neurons play a crucial role in regulating metabolic status, longevity, and overall health. The brain, particularly the hypothalamus, plays a significant role in regulating aging and longevity through cell non-autonomous mechanisms. Understanding these signaling pathways in the brain can provide insights into potential interventions for age-related issues. For more information, please refer to the provided link: https://doi.org/10.1186/s12576-024-00934-3.