Physical Fitness Influences Brain Health in Part via Effects on Microglia
Microglia are specialized immune cells in the central nervous system responsible for various functions, including synaptic management. Recent research highlights their role in aging and neurodegenerative diseases, where strategies to modulate their behavior hold promise. Physical fitness has been linked to improved cognitive function and slowed cognitive aging, partially through positive changes in microglia activity.
It is widely recognized that physical exercise can benefit brain health and cognitive function. While the impact on neuronal connections has been studied, recent focus has shifted to how exercise affects inflammation and the immune response in the central nervous system.
Microglia play a crucial role in regulating inflammatory processes and brain homeostasis. Research suggests that physical activity can influence microglia activity in various animal models, showcasing the potential therapeutic benefits of engaging in exercise.
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