Neurogenesis, the formation of new neurons from neural stem cells, is crucial for memory, learning, and brain recovery. Despite consensus on adult neurogenesis, debates persist due to limited human brain data and reliance on rodent studies. A recent study highlights a significant decline in neurogenesis with age in rodents, questioning its functional relevance in cognitive processes. The findings suggest a need for a reevaluation of the role of neurogenesis in age-related cognitive decline, emphasizing changes in existing neural networks. This study sheds light on the declining numbers of functional neurons in aging rodents and the challenges of extrapolating rodent data to humans.
A Steep Fall in Neurogenesis Over the Course of Adult Life in Mice and Rats – Fight Aging!
