More on P2Y6R Inhibition as a Strategy to Reduce Synaptic Loss in the Brain – Fight Aging!

Recent research has shown that inhibiting P2Y6R in microglia can help prevent the excessive destruction of synapses in the aging brain. This process is crucial for maintaining brain function, especially in relation to memory. While the exact reasons for this aggressive removal of synapses during aging are not fully understood, inhibiting P2Y6R shows promising results in reducing synaptic loss. This approach is still in the early stages of development and further evidence is needed to determine its effectiveness as a therapeutic strategy. The link provided offers more insights on this topic: https://doi.org/10.18632/aging.205887.