Researchers have found that variations in the gut microbiome can impact LDL-cholesterol levels, ultimately affecting the risk of cardiovascular disease. By analyzing data from the Framingham Heart Study, they discovered that bacteria like Oscillibacter play a key role in metabolizing cholesterol, leading to lower levels in individuals with higher levels of this microbe. This groundbreaking research opens up new possibilities for interventions that manipulate the microbiome to reduce cholesterol levels and lower the risk of heart disease.
The study also identified another cholesterol-lowering gut bacteria, Eubacterium coprostanoligenes, which works synergistically with Oscillibacter to decrease cholesterol levels. By studying how different microbial communities interact to influence human health, researchers hope to develop new strategies for preventing cardiovascular disease. These findings pave the way for innovative approaches to maintaining heart health through targeted modifications of the gut microbiome.
Link: https://www.broadinstitute.org/news/scientists-link-certain-gut-bacteria-lower-heart-disease-risk
