Alzheimer’s disease, characterized by memory loss and confusion, is linked to the formation of plaques and tangles in the brain. These neurodegenerative changes lead to the death of neurons, impacting cognitive function. Recent research suggests a connection between Alzheimer’s and gum disease, specifically the bacteria Porphyromonas gingivalis. Studies have shown a correlation between oral health and cognitive decline, highlighting the importance of maintaining good oral hygiene.
How Does Plaque Buildup Impact The Brain?
Plaque buildup, including beta-amyloid and tau proteins, can contribute to the development of Alzheimer’s symptoms. This disease goes beyond the brain, with potential links to overall bodily health. Research is exploring the role of Porphyromonas gingivalis, a bacterium associated with gum disease, in Alzheimer’s pathogenesis.
The Bacteria In Question?
Porphyromonas gingivalis, commonly found in oral and other bodily sites, has been implicated in Alzheimer’s development. Studies have shown a connection between gum disease, tooth loss, and cognitive decline, reinforcing the importance of oral health in preventing neurodegenerative diseases like Alzheimer’s.
What Did Studies Find?
Research has revealed a potential link between Porphyromonas gingivalis and Alzheimer’s pathogenesis. Recent studies suggest that chronic exposure to this bacterium may increase the risk of cognitive decline in later life, emphasizing the need for maintaining good oral hygiene practices.
Confirmations Made
Recent studies have provided strong evidence linking Porphyromonas gingivalis to Alzheimer’s and suggesting potential small molecule therapies for disease management. Understanding the role of this bacterium in Alzheimer’s development could pave the way for new preventive measures.
What’s Next?
While a cure for Alzheimer’s remains elusive, research on the link between Porphyromonas gingivalis and the disease offers hope for preventive strategies. Maintaining good oral health, along with other lifestyle factors like sleep, learning, exercise, and nutrition, may help reduce the risk of developing Alzheimer’s.
Sources
- Harvard Health Letter. (March 2018) Gum disease and heart disease: The common thread. https://www.health.harvard.edu/heart-health/gum-disease-and-heart-disease-the-common-thread
- Cortexyme announces publication of foundational data for groundbreaking approach to treating Alzheimer’s disease in Science Advances. Retrieved from (2019 January 23). https://www.eurekalert.org/pub_releases/2019-01/tc-cdf011819.php
- Dockrill, P. (2019, January 24). The Cause of Alzheimer’s Could Be Coming From Inside Your Mouth, Study Claims. Retrieved from https://www.sciencealert.com/new-evidence-reveals-an-unexpected-culprit-behind-alzheimer-s-disease
