The Lancet Commission has faced criticism for overlooking key ways to reduce dementia risk factors. The Alzheimer’s Prevention Expert Group has highlighted the importance of B vitamins, omega-3 fish oils, and a low-sugar diet, urging the commission to revise its report. Scientific evidence supports the health benefits of these nutrients, with studies showing that reducing homocysteine levels through nutrition interventions can significantly lower Alzheimer’s risk. Ignoring this evidence could mean missing out on preventing up to 80% of dementia cases. It is crucial for the Lancet Commission to update its recommendations to reflect the latest research on dementia prevention.