Sucrase Deficiency: Symptoms, Causes, Types, and Treatment

When brainstorming potential causes of stomach discomfort, factors like stress, IBS, or IBD may come to mind. However, a lesser-known but complex issue could be sucrase deficiency. This condition affects the body’s ability to digest sugar and carbs. Sucrase is a digestive enzyme produced in the small intestine, responsible for breaking down sucrose into glucose and fructose for absorption. A deficiency in sucrase can lead to gastrointestinal distress, causing symptoms like cramps, bloating, gas, and diarrhea. Sucrase deficiency can be temporary in adults, often triggered by conditions like infections, IBD, or malnutrition. It can also be inherited in children as congenital sucrase-isomaltase deficiency. Diagnosis typically involves an esophagogastroduodenoscopy. Foods rich in sucrose, maltose, lactose, or natural sugars can trigger symptoms, and managing the condition may require enzyme supplements like Sucraid prescribed by a healthcare professional. Working with a dietitian to understand body’s response to different foods can also help manage symptoms effectively. It is essential to consult a healthcare professional for proper diagnosis and treatment of sucrase deficiency.